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No history of previous major diseases, drug addiction, alcoholism was obtained. Atenolol alone produced an antidepressant effect and potentiated the antidepressant action of alprazolam. Intravenous IV Nikethamide was given repeatedly; urget intubation was performed and patient was kept on Mechanical ventilation. Aggressive responding increased in all groups in response to provocation but some stress response dampening was shown after both alcohol and alprazolam on the psychophysiological measures and after alprazolam on subjective ratings of anxiety.
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